Question

All of the following occur after B cells leave the bone marrow except _________

a. Production of memory B cells
b. Differentiation into plasma cells
c. Recirculation between lymph, blood and secondary lymphoid tissues
d. Receptor editing

Answer 1

Receptor editing is the correct answer as it occurs during the B cell maturation phase within the bone marrow while plasma cell differentiation, memory B cell production, and recirculation in the lymphatic system occur after they leave the bone marrow.

Step-by-step explanation:

The question pertains to B cell maturation and what does not occur after B cells leave the bone marrow. In the context of Biology, when B cells leave the bone marrow, several events unfold as part of the immune response.

These B cells can differentiate into plasma cells and memory B cells, as well as participate in recirculation between the lymph, blood, and secondary lymphoid tissues. However, receptor editing does not occur after B cells leave the bone marrow; this process happens during the maturation phase within the bone marrow to ensure self-reactive B cells are eliminated or their receptors are modified to prevent autoimmunity. This is the negative selection part of the B cell maturation process meant to minimize the risk of autoimmune diseases.

Answer 2

The process that does not occur after B cells leave the bone marrow is receptor editing, which happens during their maturation phase within the bone marrow to minimize autoimmunity.

Step-by-step explanation:

The student's question addresses the processes that occur after B cells leave the bone marrow. Among the options listed:
a. Production of memory B cells
b. Differentiation into plasma cells
c. Recirculation between lymph, blood, and secondary lymphoid tissues
d. Receptor editing
The mentioned correct option in the final answer that does not occur after B cells leave the bone marrow is receptor editing. Receptor editing happens during the maturation of B cells within the bone marrow, where self-reactive B cells can modify their receptors to avoid targeting the body's own cells, thus minimizing the risk of autoimmunity.

After exiting the bone marrow, B cells can differentiate into plasma cells or memory B cells. Plasma cells are responsible for producing antibodies, while memory B cells are crucial for mounting faster and stronger responses upon subsequent exposures to the same antigen. B cells also recirculate between lymph, blood, and secondary lymphoid tissues as part of their immune function.