Question

Which of the following is NOT a signal that originates from a successful rearrangement of a chain and the pre-T cell receptor?

a. Stimulates proliferation.
b. Stimulates expression of either CD4 or CD8 co-receptors.
c. Stops any additional TCR chain locus rearrangement.
d. Signals to become permissive for chain rearrangement.

Answer 1

The signal that originates from a successful rearrangement of a chain and the pre-T cell receptor, which is NOT mentioned in the options provided, is that it signals to become permissive for chain rearrangement.

Step-by-step explanation:

The signal that originate from a successful rearrangement of a chain and the pre-T cell receptor, which is NOT mentioned in the options provided, is that it signals to become permissive for chain rearrangement.

In the process of T cell development, successful rearrangement of the T cell receptor chains leads to the expression of either CD4 or CD8 co-receptors and the cessation of any additional rearrangement of the T cell receptor chain locus.

Therefore, the correct answer is (d) Signals to become permissive for chain rearrangement.