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Matching: Inhibitory receptor that prevents naive B cells from becoming activated

a. CD28
b. CD40
c. PD-1
d. BCR

User Mushi
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1 Answer

3 votes

Final answer:

PD-1 is the inhibitory receptor that prevents naive B cells from becoming activated, ensuring proper regulation of the immune response and prevention of autoimmunity. Option c.

Step-by-step explanation:

The inhibitory receptor that prevents naive B cells from becoming activated is c. PD-1 (Programmed cell death protein 1). PD-1 is an inhibitory receptor expressed on the surface of B cells (among other cells) which, when engaged, delivers a signal that suppresses the immune response, including the activation and proliferation of B cells.

This mechanism is important to prevent autoimmunity and to regulate the immune response, ensuring that it does not become overactive.

Options a. CD28, b. CD40, and d. BCR (B-cell receptor) are not typically considered inhibitory; rather, CD28 and CD40 are co-stimulatory molecules involved in the activation of T cells and B cells, respectively, while BCR is the receptor on B cells that recognizes specific antigens. Option c.

User Christian Schmitt
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