72.1k views
4 votes
For which of the following diagnostics is low-power magnification on the microscope not used?

a. To estimate platelet numbers
b. To detect the presence of rouleaux
c. To detect RBC agglutination
d. To detect clumping of platelets

User Gmslzr
by
8.0k points

1 Answer

3 votes

Final answer:

In diagnostics, low-power magnification is generally not used to detect clumping of platelets as it requires higher magnification to be clearly observed. The use of oil immersion lenses and agglutination assays are critical for detecting cellular details and immune responses in blood samples.

Step-by-step explanation:

The question pertains to the use of low-power magnification in microscopy for specific diagnostic purposes. When conducting a blood smear analysis using microscopy, low-power magnification is typically not sufficient to detect clumping of platelets. Clumping of platelets, also known as platelet aggregation, would require higher magnification to be seen clearly. This process can indicate various health conditions, including the presence of certain diseases or the response to certain medications. Low-power magnification is more commonly used for initial scans to evaluate the general appearance of red blood cells and platelets and in some cases, to estimate platelet numbers, detect the presence of rouleaux, and assess red blood cell agglutination.

However, to observe the internal structures or the detailed morphology of cells such as clumped platelets, higher magnifications with the use of oil immersion and special stains are typically required. For diagnostics like observing detailed cellular structures or the results of agglutination assays carried out in microtiter plates, higher magnifications provide the necessary detail to analyze these microscopic changes accurately. The uses of the oil immersion lens and methods like agglutination assays are essential in clinical diagnostics for the detection of antibodies or the presence of certain antigens.

User Andrewjamesbowen
by
7.6k points