Question

The most common inherited coagulation disorder of domestic animals is:

a. Anticoagulant rodenticide toxicity.

b. Hemophilia.

c. Thrombocytopenia.

d. Von Willebrand disease.

Answer 1

The most common inherited coagulation disorder of domestic animals is Von Willebrand disease, characterized by a deficiency in von Willebrand factor. Unlike hemophilia, which involves a genetic deficiency in clotting factors VIII or IX, Von Willebrand disease affects platelet adhesion.

Step-by-step explanation:

The Most Common Inherited Coagulation Disorder of Domestic Animals

The most common inherited coagulation disorder of domestic animals is Von Willebrand disease. This is different from hemophilia, which is a genetic disorder characterized by inadequate synthesis of clotting factors. While hemophilia typically affects the production of factor VIII or IX and is linked to the X chromosome, Von Willebrand disease is caused by a deficiency in von Willebrand factor, which is crucial for platelet adhesion.

Options like anticoagulant rodenticide toxicity and thrombocytopenia do not represent genetic disorders; the former is a type of poisoning and the latter is a condition involving an insufficient number of platelets. The inherited nature of Von Willebrand disease, along with its relative frequency compared to other clotting disorders, makes it the correct answer to the student's question.

Therefore, the correct answer is d. Von Willebrand disease. This disease is not only the most common inherited disorder in animals but also in humans and affects the ability of blood to clot efficiently.

Answer 2

The most common inherited coagulation disorder of domestic animals is Von Willebrand disease. It is a genetic condition that affects the blood's clotting ability due to a deficiency of the Von Willebrand factor, different from hemophilia, which is less common in these animals.

Step-by-step explanation:

The most common inherited coagulation disorder of domestic animals is Von Willebrand disease. This condition affects the blood's ability to clot and is similar to hemophilia in humans. Von Willebrand disease results from a deficiency of the Von Willebrand factor, which is crucial for platelet adhesion.

Unlike anticoagulant rodenticide toxicity, which is caused by exposure to rat poison, or thrombocytopenia, which involves low platelet count, Von Willebrand disease is a genetic condition and, hence, inherited. While hemophilia is a well-known genetic disorder characterized by inadequate synthesis of clotting factors, it is not as common in domestic animals as Von Willebrand disease.

Hemophilia in humans is the lack of clotting factors in the blood, primarily factor VIII in hemophilia A, or factor IX in hemophilia B, and is typically inherited via the X chromosome. Medication consisting of infusions of clotting factors can help manage hemophilia. However, in domestic animals, when considering inherited coagulation disorders, Von Willebrand disease is recognized as the most prevalent.