Final answer:
Mutations in the Rs gene usually result in resistance to insulin. This can lead to autosomal recessive disorders like Donohue syndrome or Leprechaunism, as well as Rabson-Mendenhall syndrome with its characteristic dental and glandular abnormalities.
Step-by-step explanation:
Mutations in the Rs gene usually result in resistance to insulin.
Rs gene mutations can lead to autosomal recessive disorders such as Donohue syndrome or Leprechaunism, where the insulin receptor is non-functional.
These mutations can also cause a less severe disorder called Rabson-Mendenhall syndrome, characterized by abnormal teeth, enlarged gums, and an enlarged pineal gland.