Final answer:
During pregnancy, the placenta produces hPL, which decreases the effectiveness of insulin. As a result, insulin needs increase to maintain normal blood sugar levels.
Step-by-step explanation:
The nurse informs the client that her insulin needs will increase during pregnancy because the placenta produces hPL, which decreases the effectiveness of insulin. High levels of hPL in the blood make the body less responsive to insulin, resulting in an increase in insulin needs to maintain normal blood sugar levels. This is because insulin helps to regulate blood sugar levels by allowing glucose to enter the cells for energy.