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For people with a family history of heart disease or cancer, what is the influence of their genetic makeup

User Anuj Garg
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Final answer:

Genetic factors like specific inherited mutations can greatly increase the risk of heart disease and cancer in individuals with a family history. Consulting a genetic counselor for testing is recommended, as in the case of Rebecca and her Ashkenazi Jewish heritage. Lifestyle choices also contribute to the risk and management of heart disease.

Step-by-step explanation:

For individuals with a family history of heart disease or cancer, their genetic makeup significantly influences their risk of developing these conditions.

Certain inherited risk factors and mutations, such as BRCA1 and BRCA2 in relation to breast and ovarian cancer, can greatly increase the likelihood of developing these diseases.

It is essential for such individuals, like Rebecca in the case study, to consult a genetic counselor who may recommend genetic testing to assess their risk more accurately.

This is particularly important for ethnic groups, such as Ashkenazi Jews, who have a higher prevalence of specific genetic mutations linked to cancer.

Although genetic predisposition plays a critical role in the development of certain diseases, lifestyle choices also have a significant impact on heart disease. By adopting a healthier lifestyle, individuals can slow or prevent the onset of heart disease even if they have a genetic predisposition.

User David Lasry
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