Final answer:
The nervous and endocrine systems are the two primary organ systems responsible for regulating activities in the human body, with the former controlling all bodily activities and the latter secreting hormones for regulation.
Step-by-step explanation:
The two organ systems that have the primary responsibility for regulating activities in the human body are the nervous and endocrine systems.
The nervous system controls virtually all body activities, including both voluntary and involuntary functions, which are managed by its two divisions: the somatic and autonomic nervous systems. The autonomic nervous system further splits into sympathetic and parasympathetic divisions, which regulate the body's fight-or-flight and rest-and-digest responses, respectively.
Similarly, the endocrine system works in tandem with the nervous system by secreting hormones into the bloodstream to regulate various bodily functions such as growth, metabolism, and reproduction. Therefore, the answer to the student's question is b) nervous and endocrine.