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What does intramolecular cyclization of a hydroxy aldehyde form?

User Buthrakaur
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Final answer:

Intramolecular cyclization of a hydroxy aldehyde forms a cyclic hemiacetal, which is a more stable form than the reactants.

Step-by-step explanation:

Intramolecular cyclization of a hydroxy aldehyde forms a cyclic hemiacetal. When an alcohol and carbonyl group react with each other within the same molecule, they form a five- or six-membered cyclic hemiacetal. This cyclic form is more stable than the reactants.

For example, glucose can interconvert between its open chain aldehyde form and six-membered cyclic hemiacetal form.

User Neil Albrock
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