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Which ratio of NADH to NAD+ in solution will generate the largest positive redox potential?

(a) 1:10
(b) 10:1
(c) 1:1
(d) 5:1

1 Answer

4 votes

Final answer:

The largest positive redox potential is reached with a high NADH to NAD+ ratio; specifically, a 10:1 ratio

Step-by-step explanation:

The coorect option : b

The largest positive redox potential in a solution will be generated with a high ratio of NADH to NAD+. Therefore, 10:1 will generate the largest positive redox potential since a higher concentration of the reduced form (NADH) relative to the oxidized form (NAD+) indicates a greater ability to donate electrons hence a higher redox potential. According to the Nernst equation, the redox potential is directly related to the ratio of reduced to oxidized species, with a larger ratio of NADH/NAD+ leading to a more positive potential. Consequently, understanding the role of NAD+/NADH in cellular metabolism is essential, as NAD+ is a key oxidizing agent that accepts electrons during glycolysis and the Krebs cycle, getting reduced to NADH.

This NADH can then be utilized in the electron transport chain, ultimately contributing to the production of ATP, the energy currency of the cell.The ratio of NADH to NAD+ in solution that will generate the largest positive redox potential is In redox reactions, NAD+ acts as an oxidizing agent and accepts electrons and protons from organic molecules, getting reduced to NADH. The higher the concentration of NADH compared to NAD+ in a solution, the stronger the reducing power and thus the more positive the redox potential.

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