Final answer:
Vesicles fuse with membrane enclosed endosomes to mature into lysosomes where imported material is digested through vesicle fusion with lysosomes.
Step-by-step explanation:
Vesicles fuse with membrane enclosed endosomes which mature into lysosomes where imported material is digested. This process is called vesicle fusion with lysosomes. Once internalized, the coated vesicles lose their clathrin and associated adaptor protein coat. The uncoated vesicle fuses with an early endosome to form a sorting vesicle (i.e., late endosome). Sorting vesicles separate imported content from the receptors that are recycled to the membrane. In the vesicle that remains, now a lysosome, digestive enzymes catalyze hydrolysis of the vesicle contents. The digest products are then released for cellular use.