Final answer:
The three-dimensional structures of release factors resemble RNA molecules. X-ray crystallography is used to determine ligand-target complex structures, including release factors. Recognizing similarities to simpler molecules helps predict molecular geometries.
Step-by-step explanation:
The three-dimensional structures of release factors resemble the structures of RNA molecules.
In RNA Tethering screen studies, disulfide-containing small molecules were used to determine the structures of ligands when bound to their macromolecular targets. X-ray crystallography is an experimental technique used to obtain high-quality 3D structures of ligand-target complexes, including release factors. Recognizing similarities to simpler molecules can help predict the molecular geometries of more complex molecules.
SEO keywords: release factors, RNA molecules, ligands, X-ray crystallography, molecular geometries, complex molecules