Final answer:
Inosine (option D) is the nucleotide that allows for wobble in translation in anticodons by base pairing with U, C, and A. This flexibility enables some tRNAs to recognize multiple codons but still carry the same amino acid.
Step-by-step explanation:
The nucleotide that can allow for wobble in translation in anticodons is inosine (D).
Wobble base pairing occurs between the third nucleotide of the codon on the mRNA and the first nucleotide of the anticodon on the tRNA. Inosine is a modified base that can base pair with three different nucleotides: U (uracil), C (cytosine), and A (adenine). This flexibility in base pairing allows for wobble and helps to explain why some tRNAs can recognize multiple codons with different nucleotide sequences but still carry the same amino acid.
For example, in the case of arginine, there are six different codons that can code for arginine, but only four different types of tRNAArg are needed because one of the tRNAArg molecules contains the anticodon (3') GCI (5'), which can base pair with three different codons for arginine due to the wobble at the third position.