Final answer:
Freeze-fracture replication is the technique that allows an investigation of the microheterogeneity of a membrane and visualization of localized differences in different parts of the membrane microscopy can then be used to observe the features of the interior and exterior membrane surfaces.
Step-by-step explanation:
The technique that allows an investigation of the microheterogeneity of a membrane and allows for the visualization of localized differences in different parts of the membrane is freeze-fracture replication. This technique involves freezing the membrane in water and then chipping the ice, causing the membrane to split along a line of least resistance. Scanning electron microscopy can then be used to observe the features of the interior and exterior membrane surfaces.
Freeze-fracture replication is the technique that allows an investigation of the microheterogeneity of a membrane and visualization of localized differences in different parts of the membrane microscopy can then be used to observe the features of the interior and exterior membrane surfaces.