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How many Dß-Jß rearrangements are possible in a normal human thymocyte?

A. 2
B. 6
C. 4
D. 40
E. None of the above

User Supermitch
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1 Answer

6 votes

Final answer:

In a normal human thymocyte, there are 26 possible Dß-Jß rearrangements, calculated by multiplying the two different Dß segments with each of the 13 different Jß segments.

Step-by-step explanation:

In a normal human thymocyte, Dß-Jß rearrangements are crucial for the development of the ß chain of T-cell receptors (TCRs). Based on the genetic information provided, there are two different Dß segments and 13 different Jß segments. Since each Dß segment can potentially rearrange with any of the Jß segments, the maximum number of Dß-Jß rearrangements possible in a normal human thymocyte is found by multiplying the number of Dß segments by the number of Jß segments. Therefore, there are 2 (Dß) x 13 (Jß) = 26 possible Dß-Jß rearrangements.

User Tayyab Amin
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