Final answer:
The statement regarding one-to-one communication between neurons in the CNS is false; neurons can form multiple synaptic connections and communicate with many neurons.
Step-by-step explanation:
The statement that most communication between neurons in the central nervous system is one-to-one, where one presynaptic neuron communicates to just one postsynaptic neuron, is false.
Neuronal communication is complex, and often involves one neuron connecting to and affecting many other neurons. Synaptic connections can form between axon terminals and many dendritic spines. The dendrites of a single neuron, such as a Purkinje cell in the cerebellum, can be contacted by as many as 200,000 other neurons.
Synapses are the specialized junctions through which neurons signal to each other and to non-neuronal cells, such as those in muscles or glands. This allows for complex signaling pathways in the central nervous system that contribute to the processing, integration, and response of intricate neural functions.