Question

T-cell receptors will typically bind antigen using multipoint attachment, which is achieved using two opposing human cell surfaces.

a. True
b. False

Answer 1

The statement regarding T-cell receptors using multipoint attachment involving two opposing human cell surfaces is false.

Step-by-step explanation:

The statement that T-cell receptors will typically bind antigen using multipoint attachment that is achieved using two opposing human cell surfaces is false. T-cell receptors are present on the T-cell surface and recognize processed antigens that are presented by MHC (Major Histocompatibility Complex) molecules on the surface of antigen-presenting cells (APCs). Helper T cells, which are CD4+, release cytokines while cytotoxic T cells, which are CD8+, kill infected cells.

It is also important to note that contrary to one of the false statements provided, MHC II is not a receptor found on most body cells; rather, it is found on certain immune cells like macrophages, dendritic cells, and B cells, which are APCs. MHC I is present on nearly all nucleated cells of the body. When B cells encounter their specific antigen, they require additional signals from T cells to become fully activated. This sophisticated immune response ensures precise antigen recognition and subsequent immune activation.