Question

Which of the following pairs of antibodies and their effector functions is paired incorrectly?

a. IgG : most commonly observed within the lymph & blood, of which 4 subclasses exist
b. IgA : can be monomeric or dimeric, and is the isotype made in greatest amount
c. IgM : a pentamer predominantly found in mucosal secretions
d. IgE : primarily responsible for the initiation of allergic responses
e. IgD : when present on the surface of a B cell, the B cell is considered mature

Answer 1

The pair of antibodies and their effector functions that is paired incorrectly is c: IgM . IgM is incorrectly paired with mucosal secretions, as it is typically a blood plasma pentamer and the first antibody secreted during primary immune responses; IgA is associated with mucosal secretions.

Step-by-step explanation:

A pentamer predominantly found in mucosal secretions. In fact, IgM is usually found in the blood plasma as a pentamer and it is the first antibody type that is produced and secreted by B cells during primary immune responses.

IgM can also be found as a membrane-bound monomer on the surface of naive B cells. The primary location for IgA, especially its dimeric form, is within mucosal secretions where it helps protect against pathogens in the digestive and respiratory tracts.