Question

What is the initial location of B-cell and T-cell development?

A. Blood for B cell and thymus for T cell
B. Bone marrow for both B cell and T cell
C. Bone marrow for B cell and thymus for T cell
D. Secondary lymphoid organs for B cell and thymus for T cell
E. Thymus for both B cell and T cell

Answer 1

B cells mature in the bone marrow and T cells mature in the thymus after initially developing from stem cells in the bone marrow. The correct response to the question about the initial location of B-cell and T-cell development is bone marrow for B cell and thymus for T cell, or option C.

Step-by-step explanation:

The initial location of B-cell and T-cell development is crucial for understanding the adaptive immune response. Both types of lymphocytes originate from hematopoietic stem cells in the bone marrow. For B cells, maturation occurs in the bone marrow itself, which is why they are named B cells for "bone."

On the other hand, after their initial formation in the bone marrow, T cells migrate to the thymus, a primary lymphoid organ, where they mature. Therefore, the correct answer is Bone marrow for B cell and thymus for T cell, which corresponds to option C.