Final answer:
Atorvastatin (Lipitor) and Rosuvastatin (Crestor) are the two statins which decrease LDL, increase HDL and decrease triglycerides, thus improving lipid profiles and aiding in cardiovascular disease management.
Step-by-step explanation:
The two statins that affect lipid profiles by decreasing low-density lipoprotein (LDL), increasing high-density lipoprotein (HDL), and decreasing triglycerides (TGs) are Atorvastatin (Lipitor) and Rosuvastatin (Crestor). Statins work as inhibitors of the enzyme HMG-CoA reductase which is responsible for the synthesis of cholesterol from lipids in the body. By inhibiting this enzyme, statins effectively reduce the body's cholesterol production leading to improved lipid profiles. This is particularly beneficial in managing and preventing cardiovascular diseases.