Final answer:
Toxic pest control substances and poisons should be used with caution, only after other measures have failed and by adopting the least disruptive means possible.
Step-by-step explanation:
Toxic pest control substances and poisons should only be used as a last resort when ecologically based control measures are not effective. It is crucial to select and apply pesticides in a manner that minimizes environmental disturbance, preferring products that are non-persistent and targeting their application as precisely as possible. Utilization of such substances must account for the potential evolution of resistance in target species, economic costs, and the possibility of substantial non-target impacts, which might include environmental degradation and health risks to humans and wildlife.
While pesticides play a significant role in the protection of crops and controlling pests, their application raises concerns. For example, though 99 percent of all pesticide poisoning cases happen in developing countries where regulations may be weak, pesticides continue to be vital in managing pests worldwide. Therefore, it is important to use pesticides judicially, only after other measures fail, and to apply them responsibly to minimize risks to human health and the environment.