Final answer:
Out of the 14 known eukaryotic DNA polymerases, pol δ (delta) and pol ε (epsilon) are mainly responsible for nuclear DNA replication, making the correct answer b) 15 and 3.
Step-by-step explanation:
The correct answer to the question of how many eukaryotic DNA polymerases there are, and how many of them replicate almost all nuclear DNA is: b) 15 and 3.
There are a total of 14 known eukaryotic DNA polymerases, of which five are known to have major roles during replication. These are pol α (alpha), pol β (beta), pol γ (gamma), pol δ (delta), and pol ε (epsilon).
However, it is pol δ (delta) and pol ε (epsilon) that are largely responsible for the replication of nuclear DNA.