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Which is NOT the function of eukaryotic alpha DNA polymerase?

a)Makes RNA primer
b)Tethers primase to catalytic subunit A
c)Elongates DNA
d)Extends RNA primer by making short DNA (iDNA)

1 Answer

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Final answer:

The function of eukaryotic alpha DNA polymerase that is NOT true is 'Tethers primase to catalytic subunit A'. The polymerase does make RNA primers, elongate DNA, and extend the RNA primer by making short DNA, but the tethering function is not a part of its role. Therefore, correct option is b.

Step-by-step explanation:

The function of eukaryotic alpha DNA polymerase that is NOT true is (b) Tethers primase to catalytic subunit A. Eukaryotic alpha DNA polymerase has several functions, including:

  • Makes RNA primer
  • Elongates DNA
  • Extends RNA primer by making short DNA (iDNA)

However, it does not tether primase to catalytic subunit A. This function is typically associated with the multi-protein complex at the replication fork, where different proteins and enzymes work in concert for DNA replication.

The other functions listed are integral to the DNA replication process in eukaryotic cells. For example, primase synthesizes a short RNA primer that provides a starting point for DNA polymerase to begin synthesis.

The alpha DNA polymerase is then responsible for the elongation of the new DNA strand by adding nucleotides to the primer, creating the daughter strands of DNA.

User Jon Jones
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