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With patch-clamp recordings, it is possible to study ion transport through a single molecule of a channel protein.

a. True
b. False

User Davenpcj
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Final answer:

Patch-clamp recordings can measure the ion transport through a single molecule of a channel protein, which is essential for understanding how ion channels function in various physiological processes.

Step-by-step explanation:

True: With patch-clamp recordings, it is indeed possible to study ion transport through a single molecule of a channel protein. The patch-clamp technique is an incredibly sensitive method used to measure ionic currents and membrane potentials, even at the level of a single channel protein.Channel proteins provide a pathway for ions like Na+ and K+ to move across the cell membrane, with their movement contributing to the establishment of action potentials. These proteins can be gated, meaning their opening and closing are controlled by various stimuli, such as ligands, changes in voltage, mechanical force, or temperature. Voltage-gated channels, for instance, play a crucial role in electrical signaling in nerve and muscle cells.

Patch-clamp recordings allow researchers to observe the activity of these channels directly, offering insights into how they function under different conditions. The technique can differentiate between different kinds of ion channels, including voltage-gated, ligand-gated, and mechanically-gated channels.This allows for the measurement of ion currents passing through a single ion channel. By studying these ion currents, researchers can gain insights into the function and properties of specific ion channels.

User Barry Carlyon
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