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Which type of antigen-presenting cell is most important for activating naive T cells?

A. Macrophage
B. Dendritic cell
C. Endothelial cell
D. B lymphocyte
E. Epithelial cell

User Tobonaut
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1 Answer

3 votes

Final answer:

Dendritic cells are the most important antigen-presenting cells for activating naive T cells due to their proficiency in capturing, processing, and presenting antigens in the lymph nodes to initiate the immune response.

Step-by-step explanation:

The type of antigen-presenting cell most important for activating naive T cells is B. Dendritic cell.

In the immune system, antigen-presenting cells (APCs) play a crucial role in activating T cells, which are vital for the cell-mediated immune response. Among APCs, dendritic cells are the most effective at activating naive T cells. They excel in capturing antigens, processing them, and presenting them on their surface alongside Major Histocompatibility Complex (MHC) class II molecules. This facilitates the recognition and engagement of naive T cells, specifically helper T cells, thereby initiating the immune response. The presentation of antigens by dendritic cells occurs mainly in the lymph nodes, where T cell populations are high, allowing for efficient T cell activation. While macrophages and B cells also have the ability to act as APCs, dendritic cells are specially equipped for this task and are considered the most proficient at priming naive T cells during first-time pathogen exposure, such as in early antiviral immune responses. Hence, understanding the pivotal role of dendritic cells in T cell activation is essential for comprehending the intricacies of the adaptive immune system.

User Torpederos
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