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What surface markers are found on regulatory T cells?

A. CD4 and CD25
B. CD8 and CD25
C. CD8 and CD16
D. CD4 and CD8

User Shiori
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1 Answer

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Final answer:

Regulatory T cells express the surface markers CD4 and CD25, and also the transcription factor FOXP3. They are essential for maintaining immune tolerance and preventing autoimmune diseases by suppressing other T cell immune responses.

Step-by-step explanation:

Regulatory T cells, also known as Treg cells or suppressor T cells, are a subset of T cells that are critical for maintaining immune tolerance and preventing autoimmune diseases. The surface markers found on regulatory T cells are CD4 and CD25.

While helper T cells are also characterized by CD4, regulatory T cells uniquely express CD25 along with the transcription factor FOXP3, which is critical for their function.

These cells play a crucial role in the immune system by suppressing other T cell immune responses, thereby preventing uncontrolled clonal expansion that could lead to autoimmunity and other medical issues.

User Mike Christensen
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