Final answer:
Dendritic cells utilize a non-receptor mediated form of recognition called cross-presentation, a unique capability of internalizing extracellular antigens and presenting them on MHC I molecules to CD8+ T cells.
Step-by-step explanation:
The one non-receptor mediated form of recognition for a dendritic cell is through a pattern known as cross-presentation. Dendritic cells are capable of internalizing extracellular antigens and presenting them on MHC I molecules to CD8+ T cells in a process involving phagocytosis, instead of presenting on MHC II molecules as typical for receptor-mediated recognition, this is unique among antigen-presenting cells.
Professional Antigen-presenting Cells (APCs), like macrophages, dendritic cells, and B cells, are critical in the immune response. While macrophages and dendritic cells can phagocytose pathogens, B cells focus on the production of antibodies. Crucially, dendritic cells are known for their high levels of plasticity and complexity. They express various surface receptors and utilize cross-presentation to aid in the immune response against pathogens, such as viruses, which replicate inside the cells. This mechanism allows dendritic cells to initiate a robust cytotoxic T cell response even to extracellular antigens.