Final answer:
B cells differ from other professional APCs in terms of antigen presentation by playing a primary role in antibody production and secretion, interacting with foreign pathogens using antigen-specific immunoglobulin receptors, and not requiring the participation of MHC molecules and antigen-presenting cells.
Step-by-step explanation:
B cells differ from other professional APCs in terms of antigen presentation in several ways. Unlike other APCs like macrophages and dendritic cells, B cells do not function as phagocytes but rather play a primary role in the production and secretion of antibodies. B cells also interact with foreign pathogens or their free antigens using antigen-specific immunoglobulin as receptors. Lastly, B cells can recognize native, unprocessed antigens and do not require the participation of MHC molecules and antigen-presenting cells.