Final answer:
The mechanism of cell death involving RIP1 and RIP3 kinases is called necroptosis. This form of programmed cell death occurs when apoptosis is inhibited or fails. RIP1 and RIP3 kinases promote the activation of the necrosome complex, leading to cell death.
Step-by-step explanation:
There is a mechanism of cell death called necroptosis that involves the unique kinases RIP1 and RIP3. Necroptosis is a form of programmed cell death that occurs when apoptosis is inhibited or fails. RIP1 and RIP3 kinases are key players in necroptosis, as they promote the activation of a protein complex called necrosome, which leads to cell death.
In necroptosis, RIP1 and RIP3 kinases phosphorylate each other and recruit other proteins to form the necrosome. This complex ultimately leads to the disruption of cell membrane integrity and the release of cellular contents, causing cell death.