Final answer:
Proteins synthesized on free ribosomes in the cytoplasm usually remain in the cytosol or are directed to specific intra-cellular destinations. They generally do not pass through the Golgi apparatus, which is involved in processing proteins from the rough endoplasmic reticulum.
Step-by-step explanation:
Proteins that are synthesized on free ribosomes in the cytoplasm do not typically go through the Golgi apparatus. Instead, these proteins generally remain free in the cytosol or are targeted to other locations such as the nucleus, mitochondria, or chloroplasts, depending on specific signal sequences they contain.
Unlike proteins synthesized on the rough endoplasmic reticulum, which do enter the endomembrane system for processing and distribution, cytosolic proteins are often functional within the cytoplasm itself or they contain specific sorting signals that direct them to their intracellular destinations without the need for the Golgi apparatus.