Final answer:
After DJ rearrangement, transcription occurs due to weak promoters upstream of D, resulting in the production of a functional protein.
Step-by-step explanation:
After DJ rearrangement, transcription occurs due to weak promoters upstream of D, resulting in the production of a functional protein. This statement is true.The question pertains to the process that occurs after DJ rearrangement in the immune system's development of diversity in antibodies. Specifically, it is asking about the role of promoters in initiating transcription after DJ rearrangement has occurred in the development of B cells. The statement in the question appears to be false because DJ rearrangement itself does not lead to the production of functional protein. Instead, this rearrangement is followed by V to DJ joining to create a complete variable region, which then must be transcribed and translated into a functional protein. Furthermore, the promoter regions upstream of D segments could potentially be mutated, which affects their ability to properly initiate transcription. Mutated promoters can affect the binding site for transcription factors and consequently alter the rate of transcription for adjacent genes. Increased transcription typically occurs when RNA polymerase has enhanced binding to promoter regions, either through mutations or the involvement of enhancers and transcription factors.