Question

Constant region gene for each of the following (in humans): IgM IgD IgG IgE IgA

a) α, δ, γ, ε, μ
b) μ, γ, δ, ε, α
c) δ, ε, α, μ, γ
d) γ, μ, δ, α, ε

Answer 1

The constant region gene for IgM, IgG, IgD, IgE, and IgA correspond to the heavy chains mu (μ), gamma (γ), delta (δ), epsilon (ε), and alpha (α) respectively. The correct sequence is b) μ, γ, δ, ε, α, which associates IgM, IgG, IgD, IgE, and IgA with their respective constant region genes.

Step-by-step explanation:

The student has asked to identify the constant region gene for each of the five classes of antibodies in humans: IgM, IgD, IgG, IgA, and IgE. Each class of antibodies is associated with a unique heavy chain that is denoted by a specific Greek letter. These heavy chains correspond to the constant region of the antibody molecule that determines its class or isotype.

IgM contains the heavy chain μ (mu)

IgD contains the heavy chain δ (delta)

IgG contains the heavy chain γ (gamma)

IgA contains the heavy chain α (alpha)

IgE contains the heavy chain ε (epsilon)

Therefore, the correct sequence associating these antibodies with their constant region genes is option b) μ, γ, δ, ε, α, which matches to the antibodies as IgM, IgG, IgD, IgE, and IgA respectively.