Final answer:
Plasmatoid dendritic cells are primarily found in the blood and have a crucial role in viral immune responses, while normal dendritic cells are tissue-resident antigen-presenting cells.
Step-by-step explanation:
Plasmatoid dendritic cells and normal dendritic cells are both important cell types of the immune system, but they have some differences in their functions and location. Normal dendritic cells are present in various tissues that have contact with the external environment, such as the skin, nose, lungs, stomach, and intestines. They act as antigen-presenting cells, triggering adaptive immune responses. On the other hand, plasmatoid dendritic cells are primarily found in the blood and have a crucial role in initiating immune responses to viral infections. In summary, normal dendritic cells are tissue-resident antigen-presenting cells, while plasmatoid dendritic cells are circulating immune cells that play a specific role in viral immune responses.