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How long is a typical light chain V region? how many CDRs are there in this V region?

User Asprtrmp
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Final answer:

A typical light chain V region spans from amino acids 1 to 108, and contains three complementarity-determining regions (CDRs) located at specific positions which are critical for antigen binding.

Step-by-step explanation:

The typical light chain V region is composed of the variable (VL) segment which spans from amino acid 1 to 108 from the N-terminal end. Within this VL region, there are three complementarity-determining regions (CDRs). These CDRs, also known as hypervariable regions, are crucial for the antigen-binding specificity of antibodies and consist of segments that show extreme variability. Specifically, they are found at positions 24 through 34, 50 through 56, and 89 through 97 in the light chain V region. Each CDR contains 6 to 10 amino acids that contribute to the unique antigen-binding ability of each B cell's antibody.

User Gouessej
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