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The Ku complex binds to both the coding joints and the signal joints created during VDJ recombination?

a) True
b) False

1 Answer

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Final answer:

The statement that the Ku complex binds to both coding joints and signal joints during VDJ recombination is false. The Ku complex's role is primarily in DNA repair, and it does not bind to both joints during the VDJ recombination process.

Step-by-step explanation:

The Ku complex is a protein that plays a role in DNA repair, specifically in the non-homologous end joining (NHEJ) pathway. However, in the context of V(D)J recombination, which is a mechanism used by the immune system to generate diverse antibody molecules, the role of the Ku complex is not to bind both coding joints and signal joints. V(D)J recombination involves the joining of V (Variable), D (Diversity), and J (Joining) gene segments to generate the unique variable regions of immunoglobulins, but the formation of the coding and signal joints entails different processes. Therefore, the statement that "The Ku complex binds to both the coding joints and the signal joints created during VDJ recombination" is false.

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