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Despite dendritic cells originating from both myeloid and lymphoid precursors, they are predominantly developed from which?

a) Myeloid precursors
b) Lymphoid precursors
c) Hematopoietic precursors
d) Monocytic precursors

User Davisoski
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Final answer:

Dendritic cells are predominantly developed from myeloid precursors. Myeloid stem cells in the red bone marrow give rise to various blood and immune cells, including dendritic cells. Though cells like T cells originate from lymphoid stem cells, the primary development of dendritic cells is linked to myeloid lineage.

Step-by-step explanation:

Dendritic cells, which are part of the immune system, can originate from both myeloid and lymphoid precursors. However, they are predominantly developed from myeloid precursors. Myeloid stem cells are responsible for giving rise to various formed elements of the blood, including not only red blood cells and platelets but also immune cells like dendritic cells. These myeloid precursors differentiate in the red bone marrow, which is the primary site of hematopoiesis, and this process is regulated by hematopoietic growth factors.

Lymphoid stem cells also contribute to the immune system, predominantly giving rise to different classes of lymphocytes such as T cells, B cells, and natural killer (NK) cells. It is noteworthy that T cells originate as CD4+T cell precursors in the bone marrow and then migrate to the thymus for further development. Finally, you may encounter monocytes in the circulation that can differentiate into either macrophages or dendritic cells, further illustrating the diversity of cell development within the immune system.

User Crystina
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