Final answer:
L-selectin binds to GlyCAM-1 and CD34 molecules, allowing the rolling of naive T lymphocytes.
Step-by-step explanation:
L-selectin is a cell adhesion molecule that is expressed on the surface of naive T lymphocytes. It plays a crucial role in initiating the rolling of these lymphocytes along the blood vessel walls during inflammation. It binds to specific molecules called GlyCAM-1 and CD34, which are present on endothelial cells lining the blood vessels. The molecules that L-selectin binds to, allowing the rolling of naive T lymphocytes, are GlyCAM-1 and CD34. These molecules are glycocalyx proteins that are identified as Intercellular Cell Adhesion Molecules (ICAMs), specifically engaged in the adhesion and migration processes of immune cells. Selectin family members, including L-selectin, E-selectin, and P-selectin, play a crucial role in the immune response by promoting interactions between white blood cells and the endothelium, thereby facilitating the movement of cells from the bloodstream to tissues during inflammation or immune surveillance.