Final answer:
The main difference between USB 2.0 and USB 3.0 is their data transfer speeds, with USB 3.0 being significantly faster.
Step-by-step explanation:
One significant difference between USB 2.0 and USB 3.0 is their data transfer speed. USB 2.0, also known as High-Speed USB, has a maximum data transfer rate of 480 megabits per second (Mbps), which was quite fast when it was introduced. In contrast, USB 3.0, which is also referred to as SuperSpeed USB, boasts a much higher data transfer rate of up to 5 gigabits per second (Gbps). This means that USB 3.0 is approximately ten times faster than USB 2.0, allowing for quicker transfer of large files and more efficient data handling.