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C1q is also a member of the collectin family?

a) True
b) False

1 Answer

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Final answer:

C1q is not a member of the collectin family but rather part of the complement system. Hemolytic disease of the newborn is more likely in second pregnancies because of maternal sensitization to the Rh factor. The D antigen corresponds to the Rh, not the ABO blood group system.

Step-by-step explanation:

The statement 'C1q is also a member of the collectin family' is false. C1q is a component of the complement system, specifically the classical pathway, and not a member of the collectin family. Collectins are a type of collagen-containing C-type lectins, which include molecules like mannose-binding lectin (MBL), whereas C1q is involved in immune complex recognition and plays a different role in the immune response.

Hemolytic disease of the newborn may be more likely to occur in a second pregnancy than in a first due to the immune system of the mother being sensitized to the Rh factor (if she is Rh-negative and the fetus is Rh-positive) during the first pregnancy. This can lead to the production of antibodies that can cross the placenta and attack the red blood cells of a subsequent Rh-positive fetus.

The D antigen is not part of the ABO blood group system but rather the Rh blood group system. In regards to a man donating blood to his wife, compatibility would depend on their respective ABO and Rh blood types, with additional consideration for other factors such as antibodies the recipient may have.

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