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C-reactive peptide and SAP are part of which family of proteins?

a) Interleukins
b) Collectins
c) Complement factors
d) Kinases

User Bebingando
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1 Answer

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Final answer:

CRP and SAP belong to the pentraxin family and are involved in the acute-phase immune response, particularly in activating the lectin pathway of the complement system, which forms part of the innate immune system.

Step-by-step explanation:

C-reactive peptide (CRP) and Serum Amyloid P component (SAP) are part of the pentraxin family of proteins. These proteins are involved in the acute-phase response to inflammation. The pentraxins recognize pathogens and damaged cells and initiate their elimination by interacting with the complement system and phagocytic cells.

CRP and SAP can trigger the lectin pathway of complement activation, which is part of the innate immune system. This pathway is similar to the classical pathway but is initiated by the binding of a pattern recognition molecule, such as a mannose-binding lectin or ficolins, to a pathogen, which in turn activates the complement cascade. Unlike the adaptive immune system components, such as T cells and antibodies, the complement system is a nonspecific defence mechanism that forms a key part of the innate immune response.

In contrast to cytokines like interleukins and the glycoproteins that aid in cell adhesion and red blood cell identification, which are more specific in their function, acute-phase proteins like CRP and SAP play a more generalized role in immune defence by aiding in the quick recognition and removal of pathogens and damaged cells.

User Gauthier
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