Final answer:
The level of ketone bodies in the blood increases when high levels of fatty acids are being metabolized. Ketosis occurs when an excess of acetyl-CoA is converted into ketone bodies, resulting in their accumulation in the blood. This can happen in conditions such as starvation and diabetes mellitus.
Step-by-step explanation:
The level of ketone bodies in the blood increases when high levels of fatty acids are being metabolized. In conditions such as starvation and diabetes mellitus, when cells do not receive enough carbohydrate, the rate of fatty acid oxidation increases, leading to an increase in the concentration of acetyl-CoA. The excess acetyl-CoA is converted into ketone bodies, which accumulate in the blood, resulting in a condition called ketosis.