Final answer:
In the fed state, the body always uses glucose for immediate energy and stores the excess as glycogen in the liver and muscles. Insulin facilitates glucose uptake and storage, ensuring energy homeostasis is maintained.
Step-by-step explanation:
Understanding the Fed State in Metabolism
During the absorptive state, commonly referred to as the fed state, the body digests and absorbs nutrients from the food consumed. Glucose serves as the body's primary source of energy and is used by various tissues, including the brain which relies continuously on glucose. In this state, blood glucose levels are elevated, prompting the secretion of insulin, which facilitates the uptake of glucose by the liver, muscles, and adipose tissues. Excess glucose is then stored as glycogen in the liver and muscles for later use during fasting.
In contrast, during the postabsorptive state or fasting state, the body relies on stored energy. Glycogenolysis, the breakdown of glycogen, is initiated to maintain blood glucose levels. Ketone oxidation may provide additional energy through the release of lipids and glucose, with ATP generated for the body's use. These processes ensure a continuous energy supply between meals and during overnight fasting. Thus, in the fed state, the body always uses glucose as its immediate source of fuel, storing any excess in the form of glycogen. This mechanism is crucial for maintaining energy homeostasis, allowing for smooth transitions between fed and fasting states.