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Which of the following enzymes catalyzes the conversion glucose-6-phosphate to fructose-6-phosphate?

A. Phosphoglucose isomerase
B. Hexokinase
C. Phosphofructokinase
D. HMG-CoA reductase

User Pivotal
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1 Answer

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Final answer:

Phosphoglucose isomerase is the enzyme that converts glucose-6-phosphate to fructose-6-phosphate in the glycolytic pathway.

Step-by-step explanation:

The enzyme responsible for catalyzing the conversion of glucose-6-phosphate to fructose-6-phosphate is phosphoglucose isomerase. This is a crucial step in the glycolytic pathway, where a glucose molecule is eventually split into two three-carbon molecules. The process of converting glucose-6-phosphate (a six-carbon monosaccharide with a phosphate group attached at the sixth carbon) into its isomer, fructose-6-phosphate, is an important transformation that allows for the continuation of glycolysis, which is the metabolic pathway that converts glucose into pyruvate while generating small amounts of energy in the form of ATP and NADH.