Final answer:
To fix the asymmetric distribution of small ions, changing the membrane permeability or using a semipermeable membrane that self-selects which ions can pass through, would address the issue by directly altering how ions are able to move across the membrane.
Step-by-step explanation:
In biology, specifically in the context of cellular functions, the asymmetric distribution of ions across a cell membrane can be critical for various physiological processes, such as the generation of membrane potential and cellular signaling. To fix an asymmetric distribution of small ions, one might consider changing the membrane permeability or using a semipermeable membrane. Membranes are selectively permeable due to their structure, allowing some ions or molecules to pass through while restricting others. The ability of ions to move across the membrane is often facilitated by ion channels or transporters, which can be specific to certain ions.
The usage of a semipermeable membrane, which has pores that allow only certain small molecules to pass, can help in achieving the desired distribution by preventing or allowing specific ions to migrate. Furthermore, changing the membrane permeability by altering the activity of ion channels or transport mechanisms can adjust the distribution of ions across the membrane. It's important to note that while increasing temperature can affect the movement of molecules, and adding more solute can change the concentration gradient, these methods are not directly related to fixing an asymmetric ion distribution in the context given.