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Extrapyramidal symptoms are a side effect of which of the following drugs?

a. ranitidine
b. famotidine
c. omeprazole
d. metoclopramide

1 Answer

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Final answer:

Metoclopramide, used to treat nausea and gastroparesis, is the drug among the provided options that can cause extrapyramidal symptoms due to its dopamine antagonist activity in the brain.

Step-by-step explanation:

Extrapyramidal symptoms are a side effect of certain drugs that affect the dopaminergic pathways within the central nervous system. These pathways are crucial for controlling movement and coordination. Among the options provided, metoclopramide is known to cause extrapyramidal side effects due to its dopamine antagonist properties, particularly when used in higher doses or for prolonged periods. Metoclopramide is a medication used to treat nausea, vomiting, and gastroparesis, but it can also cross the blood-brain barrier and influence dopamine receptors in the brain, leading to these side effects. The other drugs listed: ranitidine, famotidine, and omeprazole, are all associated with decreasing stomach acid production and are not typically associated with extrapyramidal side effects.

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