Final answer:
Scission in vesicle targeting and fusion describes the shedding of protein coats from vesicles before they fuse with target compartments, facilitated by V-SNARE and T-SNARE proteins.
Step-by-step explanation:
Scission in vesicle targeting and fusion refers to the process where transport vesicles that bud from a donor compartment, like the trans-Golgi network, eventually shed any protein coats, such as clathrin, in preparation for fusing with an acceptor compartment, like an endosome. This fusion event is made possible by the interaction between V-SNARE proteins on the vesicle and T-SNARE proteins on the target membrane. The resulting vesicle can then carry out its function; for example, if it becomes a lysosome, its hydrolytic enzymes can degrade vesicle contents, releasing usable molecules into the cell.