Final answer:
In the vast repertoire of the immune system, approximately 50 out of 100,000 naive T cells might be specific for a particular antigen. This low number reflects the extreme diversity of the immune system's capability to recognize a multitude of possible antigens.
Step-by-step explanation:
The subject of the question is the specificity of naive T cells to a particular antigen within the human immune system. T cells are part of the body's adaptive immune response, and each has receptors that are specific to particular antigens. Given that the human immune system can produce a highly diverse range of antibody molecules due to the unique genetic mechanisms at play, such as recombination and hypermutation, the number of T cells specific to any single antigen is very small compared to the total number of T cells.
Considering the vast number of possible antigens that T cells might encounter, estimated to be in the range of 100 million, and the fact that 100,000 naive T cells are being questioned, the expected number of T cells specific for any single given antigen will be much lower than 1,000 or 10,000. Statistically, we can infer that the correct answer is likely much smaller, such as in the dozens, which would suggest an answer of approximately 50 naive T cells out of 100,000 might be specific for a particular antigen.