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During B cell activation, 'linked recognition' refers to the idea that the B and T cell:

a) Have identical receptors
b) Recognize the same antigen
c) Interact simultaneously
d) Share MHC molecules

1 Answer

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Final answer:

Linked recognition during B cell activation refers to the simultaneous interaction between B cells and helper T cells, whereby the B cell presents an antigen and the T cell provides activation signals.

Step-by-step explanation:

During B cell activation, 'linked recognition' refers to the idea that the B and T cell interact simultaneously. This concept is central to the immune response and involves the collaboration between these two types of lymphocytes. B cells function as antigen-presenting cells (APCs), processing and presenting antigen on their surface bound to MHC class II molecules. Once the antigen is presented, the B cell requires help from a specific T cell, known as a helper T cell, which has already encountered and been activated by the same antigen. The T cell binds to the antigen-MHC complex using its receptor and activates the B cell by secreting cytokines, enabling the B cell to fully activate and produce antibodies specific to the antigen.

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