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4 votes
Which of the following transcription factors trigger an innate immune response?

A) NF-kB
B) Myc
C) CREB
D) STAT

User Asafel
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1 Answer

4 votes

Final answer:

NF-kB is the transcription factor that triggers an innate immune response by entering the nucleus to stimulate transcription after being activated through phosphorylation.

Step-by-step explanation:

Among the transcription factors listed, NF-kB is known to trigger an innate immune response. Phosphorylation of the inhibitor IK-B leads to its dissociation from NF-kB. This event allows NF-kB to enter the nucleus to stimulate transcription of genes involved in the immune response. NF-kB is not a kinase itself, but rather a transcription factor that is activated through phosphorylation. Upon activation, NF-kB binds to DNA and promotes the production of proteins necessary for the innate immune system to function effectively against pathogens like bacteria and viruses.

User Piers Karsenbarg
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